HIGH IRF8 EXPRESSION CORRELATES WITH CD8 T CELL INFILTRATION AND IS A PREDICTIVE BIOMARKER OF THERAPY RESPONSE IN ER-NEGATIVE BREAST CANCER

High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

Abstract Background Characterization of breast cancer (BC) through the determination of conventional markers such as ER, PR, HER2, and Ki67 has been useful as a predictive and therapeutic tool.Also, assessment of tumor-infiltrating lymphocytes has been proposed as an important prognostic aspect to be considered in certain BC subtypes.However, there

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Czechoslovak forest experts in Cold War Angola

The first Czechoslovak pioneers of lampada tropical and subtropical forestry appeared in the nineteenth century.Yet, only after the onset of the communist regime in Czechoslovakia in 1948, in connection with the advancing decolonization of the Global South and the culmination of the Cold War, did the dispatch of forest experts in post-colonial coun

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